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Definition of acutely : In an acute manner; sharply; keenly; with nice discrimination.

Synonyms:

sharp, sagaciously, shrewdly, very, precipitously, sapiently, astutely, aggressively

gnawingly, smartingly, disagreeably, cruelly, painfully, aggravatingly, insufferably, distressfully, hurtfully, miserably, uncomfortably, sorely, troublesomely, excruciatingly, horrendously, grievously, tryingly, distressingly, unpleasantly, torturously, piercingly, woefully, bitterly, bitingly, arduously, stingingly, offensively, annoyingly, witheringly, gruelingly, achingly, tormentingly, irksomely, odiously, irritatingly, unbearably, agonizingly

pointedly, jaggedly, spikily

hoarsely, ear-piercingly, raucously, penetratingly, screamingly, scratchily, trebly, shrilly, gratingly, jarringly, squeakily, whiningly, creakily, raspingly, stridently

cuttingly, brusquely, harshly, correctly, exactingly, intolerantly, oppressively, austerely, bluntly, rigorously, precisely, crisply, acrimoniously, leanly, matter-of-factly, strictly, abruptly, icily, imperially, fundamentally, curtly, frostily, caustically, dourly, critically, briskly, keenly, piquantly, severely, starkly, intensely, tartly, gruffly, sternly, shortly, sharply, ascetically, meticulously, sparely, rawly, acerbically, bleakly, demandingly, grimly, basically, stringently, dryly, coolly

Usage examples:

• Vivid sensation, of either pain or pleasure, makes the time seem long, as the common phrase is, because it renders us more acutely conscious of our ideas. - "The Complete Poetical Works of Percy Bysshe Shelley Volume III", Percy Bysshe Shelley Edited by Thomas Hutchinson, M. A..
• It is a pity her letters gave you the impression that she was feeling your absence so acutely. - "Antony Gray,--Gardener", Leslie Moore.
• She suffered acutely when with girls of her own age, because she felt unfit to be with them. - "Secret Bread", F. Tennyson Jesse.