AMBUSTIAL
\ˈambʌstjə͡l], \ˈambʌstjəl], \ˈa_m_b_ʌ_s_t_j_əl]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.