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Definition of baneful : Having poisonous qualities; deadly; destructive; injurious; noxious; pernicious.

Synonyms:

noisome, apocalyptical, insalubrious, perverting, hellfire, deleterious, warn, menacing, plaguey, prejudicial, grave, ominous, adverse, fateful, deadly, minacious, noxious, injurious, forbidding, subtle, lethal, pestilent, deathly, harmful, dire, unwholesome, nocuous, fire-and-brimstone, insidious, maleficent, apocalyptic, pestilential, dangerous, pestiferous, threatening, direful, minatory, unhealthful, pernicious, unlucky, mischievous, portentous, mortal, damaging, help, ruinous, luck

inadequate, irremediable, black, unsatisfactory, unsound, poor, ill-suited, invalid, wretched, defective, inadvisable, unfavorable, vile, faulty, unpleasant, wrong, displeasing, arrant, inferior

disgraceful, monstrous, destructive, sinister, devilish, heinous, bad, offensive, depraved, wicked, abominable, foul, calamitous, damnable, terrible, repulsive, evil, villainous, loathsome, reprehensible, fiendish, repugnant, hideous, atrocious, diabolical, detrimental, revolting, satanic, repellent, nefarious, sinful

hostile, nasty, venomous, spiteful, vindictive, hateful, catty, malignant, treacherous, antagonistic, vicious, ill-natured, mean, hurtful, bitter, perfidious, churlish, sullen, malicious, corrosive, malevolent, virulent, black-hearted, baleful, rancorous

cursed, contagious, ill, infectious, poisonous, cancerous

Usage examples:

• Polygamy is so bound up with heathen customs, and exerts, in their view, so entirely baneful an influence upon native society, that it must be at all hazards resisted and condemned. - "Impressions of South Africa", James Bryce.
• More baneful even than the influence of the theatre is the influence of success. - "Musicians of To-Day", Romain Rolland Commentator: Claude Landi.
• About the fourth day of the election the real excitement commenced, and the baneful system of bribery was resorted to. - "Recollections of Old Liverpool", A Nonagenarian.