CLINCHER-WORK
\klˈɪnt͡ʃəwˈɜːk], \klˈɪntʃəwˈɜːk], \k_l_ˈɪ_n_tʃ_ə_w_ˈɜː_k]\
Definitions of CLINCHER-WORK
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.