COOLIDGE TUBE

\kˈuːlɪd͡ʒ tjˈuːb], \kˈuːlɪd‍ʒ tjˈuːb], \k_ˈuː_l_ɪ_dʒ t_j_ˈuː_b]\

Definitions of COOLIDGE TUBE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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