COTAPHITE ARTERIES

\kˈɒtɐfˌa͡ɪt ˈɑːtəɹiz], \kˈɒtɐfˌa‍ɪt ˈɑːtəɹiz], \k_ˈɒ_t_ɐ_f_ˌaɪ_t ˈɑː_t_ə_ɹ_i_z]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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