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Definition of derangement:

  1. The act of deranging or putting out of order, or the state of being deranged; disarrangement; disorder; confusion; especially, mental disorder; insanity.

Synonyms:

mental unsoundness, imbalance, instability, alienation, monomania, confusedness, jumble, order, turnover, muddle, muss, unbalance, mix-up, disorderedness, scramble, overturn, psychopathy, muddle, mental illness, snafu, upset, insaneness, jumble, brainsickness, swage, tumble, overthrow, disturbance, sane, topsy-turviness.

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