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Definition of desecration : The act of desecrating; profanation; condition of anything desecrated.

Synonyms:

sacrilege, defilement, profanation, blasphemy, irreverence, sacred, study at sacrilege

degradation, ill-use, abuse, violation, ill-treatment, debauchery, debasement, misuse, despoiling, maltreatment

Usage examples:

• What a prize she would prove to Jack Redland; he thought of no other man in connection with her: the mere idea seemed desecration. - "The Second String", Nat Gould.
• The watcher awaited some mysterious punishment for this desecration. - "The Wrong Twin", Harry Leon Wilson.
• It's a desecration of the dead. - "The Abandoned Room", Wadsworth Camp.