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Definition of despise : To look down upon with disfavor or contempt; to contemn; to scorn; to disdain; to have a low opinion or contemptuous dislike of.

Synonyms:

spurn, scorn, freeze off, sneer at, respect, flout, shun, disdain, execrate, nauseate, turn down, look down on, scout, reject, look down upon, love, pooh-pooh, dislike, contemn

abominate, hate, loathe, detest, abhor

Usage examples:

• " Yes; you will despise me now. - "The Squire's Daughter", Silas K(itto) Hocking.
• No, no; she herself would despise me. - "Hurricane Hurry", W.H.G. Kingston.
• The one woman he honoured, the other he must perforce despise, and yet- such is the heart of man- he was more ready than ever to give up life, honour, a great name, and still greater destiny, so that the worthless object of his whole- hearted affection should be spared public disgrace. - "The Tangled Skein", Emmuska Orczy, Baroness Orczy.