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Definition of despite:

  1. An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.
  2. In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.
  3. Malice; malignity; spite; malicious anger; contemptuous hate.
  4. To vex; to annoy; to offend contemptuously.

Synonyms:

even with, despisal, insult, attack, outrage, scorn, patronage, recalcitrancy, indignity, condescension, offense, contumacy, resist, in defiance of, in spite of, respect, contempt, contumely, recalcitrance, disdain, defiance, slight, notwithstanding, disrespect, affront.

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