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Definition of despoil : 1. Spoil.
2. To deprive for spoil; to plunder; to rob; to pillage; to strip; to divest; - usually followed by of.
3. To strip, as of clothing; to divest or unclothe.

Synonyms:

disinvest, clean, denude, disrobe, baffle, flub, bare, deflower, peel, maraud, give, strip, transgress, vitiate, offend, break, harm, loot, outrage, foil, havoc, ravish, breach, bollocks up, go, botch up, plunder, bilk, raid, bodge, crimes, foul up, bollix up, denudate, strip down, bungle, muck up, foray, coddle, ball up, discase, mark, bumble, sack, go against, infract, bollocks, indulge, harrow, hurt, pamper, rob, go bad, scotch, blow, cocker, injure, comb, assault, undress, rape, cosset, featherbed, reave, mess up, divest, profane, cross, screw up, mollycoddle, mishandle, botch, louse up, corrupt, leach, dismantle, deprive, rifle, disfigure, bobble, baby, dishonor, dishonour, spoliate, stain, fumble, unclothe, bollix, fluff, study at ravage, muff, itch, uncase, frustrate, take its toll, impair, thwart

ruin, spoil, damage, lay waste, ravage, depredate, rend, ransack, mar, waste, pillage, wreak havoc, wreck, vandalize

excrete, deject, slop, leak

defile, debase, misuse, desecrate, maltreat, ill-treat, debauch, ill-use, degrade, abuse, violate

Usage examples:

• They have been traveling far to- day and are therefore heavy with sleep, and we can despoil them of as much as we can carry away. - "Shan Folk Lore Stories from the Hill and Water Country", William C. Griggs.
• Unfortunately, the engineer seems not often to be trained in the values of scenery and he is likely to despoil a landscape or at least to leave it raw and unfinished. - "The Holy Earth", L. H. Bailey.
• He had to persuade himself that this child of his was issue of a loving union; he had to do it violently, conjuring a vivid picture of the mother in bud, and his recognition of her young charm; the pain of keeping to his resolve to quit her, lest she should subjugate him and despoil him of his wrath; the fatalism in his coming and going; the romantic freak it had been,- a situation then so clearly wrought, now blurred past comprehension. - "The Complete Project Gutenberg Works of George Meredith", George Meredith.