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Definition of destructive : 1. Causing destruction; tending to bring about ruin, death, or devastation; ruinous; fatal; productive of serious evil; mischievous; pernicious; -- often with of or to; as, intemperance is destructive of health; evil examples are destructive to the morals of youth.
2. One who destroys; a radical reformer; a destructionist.

Synonyms:

cataclysmal, negative, devastative, hazardous, unsafe, perilous, pernicious, help, unfortunate, risky, unhealthful, caustic, annihilatory, ruinous, noisome, annihilative, blasting, perverting, obliterating, mischievous, crushing, hurtful, noxious, damning, poisonous, cataclysmic, insalubrious, ravaging, soul-destroying, adverse, erosive, dangerous, annihilating, pestilential, vitriolic, corrosive, pestiferous, withering, fateful, obscurant, wasteful, unfavorable, unwholesome

fatal, curative, lethal, internecine, dire, cancerous, murderous, incendiary, subversive, suicidal, toxic, venomous, disruptive, helpful, fell, baleful, mortal

evil, offensive, sinful, repugnant, terrible, disgraceful, calamitous, monstrous, revolting, abominable, sinister, heinous, nefarious, foul, bad, repellent, damnable, repulsive, loathsome, detrimental, hideous, wicked, baneful, atrocious, reprehensible

disastrous, deleterious, harmful, injurious, deadly, devastating, damaging, catastrophic

Usage examples:

• On account of the first- named advantage, they are largely employed upon small gears, having their teeth cut true in a gear- cutting machine; while on account of the second advantage, interchangeable wheels, which are merely required to transmit motion, may be put in gear without a fine adjustment of the pitch circle, in which case the wear of the teeth will not prove destructive to the curves of the teeth. - "Modern Machine-Shop Practice, Volumes I and II", Joshua Rose.
• Josiah wuz considerable interested in the enormous display of rifles, and all the machinery for makin' 'em, and showin' how and where the destructive instruments used in war are made. - "Samantha at the World's Fair", Marietta Holley.
• And toward these other ills we take an attitude which is not wholly destructive. - "The Sources Of Religious Insight", Josiah Royce.