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Definition of disable : 1. Lacking ability; unable.
2. To deprive of legal right or qualification; to render legally incapable.
3. To deprive of that which gives value or estimation; to declare lacking in competency; to disparage; to undervalue.
4. To render unable or incapable; to destroy the force, vigor, or power of action of; to deprive of competent physical or intellectual power; to incapacitate; to disqualify; to make incompetent or unfit for service; to impair.

Synonyms:

disenable, disqualify, damage, invalid, help, put out of action, unfit, study at maim, ability, immobilize, knock out, maim

hamper, invalidate, deaden, tamper, dull, hobble, benumb, neutralize, cripple, weaken, abrogate, hinder, botch, cramp, undermine, scotch, hamstring, vitiate, incapacitate, prostrate, handicap, sap, impair, anesthetize, enfeeble, disarm, screw up, stun, paralyze, lame, stupefy

debilitate

Usage examples:

• To disable the pilot of the opposing aeroplane will be the first object.
• He was face to face with taking a man's life or surrendering his own, and he knew the life must be taken in such a way as instantly to disable its possessor. - "Nan of Music Mountain", Frank H. Spearman.
• My chief regret is that Hilland's wound did not disable him wholly from further service in the field. - "His Sombre Rivals", E. P. Roe.