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Definition of extermination : 1. Elimination.
2. The act of exterminating; total destruction; eradication; excision; as, the extermination of inhabitants or tribes, of error or vice, or of weeds from a field.

Synonyms:

loss, ruination, demolishment, crimes, extinguishment, settlement, havoc, ruin, make, demolition, mincemeat, wastage, help, extinguishing, extinction, obliteration, experimental extinction, defunctness, quenching

destruction, vaporization, abolishment, devastation, disintegration, decimation, wreckage, desolation, holocaust, eradication, extirpation, annihilation

hanging, elimination, slaughter, purging, murder, assassination, liquidation, asphyxiation, execution, killing, snuffing, massacre, manslaughter, butchering, strangulation, removal, slaying, dispatching

Usage examples:

• They condescended to return no answer to his more than straightforward communication, save the short verbal reply concerning O'Neill: " We have given forth speach of his extermination by war." - "Irish Race in the Past and the Present", Aug. J. Thebaud.
• The ladies among us wore hats and cloaks and head- dresses obtained by wholesale massacres, ruthless trappings, callous extermination of our fellow creatures. - "The Doctor's Dilemma: Preface on Doctors", George Bernard Shaw.
• The savages seemed bent upon a war of extermination. - "The Adventures of Daniel Boone: the Kentucky rifleman", Uncle Philip.