pest, sexy, thwarting, excite, defeat, bugbear, nuisance, trial, irk, paralysis, frisky, dismay, headache, inconvenience, want, fury, resentment, irritant, thorn, vexation, anger, proscription, hassle, rage, temper, pip, randy, desire, on the pull, licking, aggravation, grief, excited, asperity, discouragement, arouse, hot, ruffle, prevention, letdown, hair shirt, bother, rub, foiling, annoyance, outrage, mood, sabotage, botheration, peeve, retardation, aggro
disappointment (part of speech: noun)
hindrance (part of speech: noun)
brake, drawback, bung, barrier, handicap, impasse, bafflement, deterrent, constraint, hindrance, snag, impedance, bottleneck, delay, complication, opposition, jam, restraint, drag, snarl, restriction, resistance, congestion, interruption, damper, impediment, mire, encumbrance, hurdle, entanglement, constipation, blockade, choke, obstacle, obstruction, tangle, plug, stoppage, burden, blockage, clog, catch, block, stop, stay, entrapment, disadvantage, crimp, dam, inhibition
discontentment (part of speech: noun)
despondence, wretchedness, angst, boredom, uncomfortableness, disquiet, exasperation, discomposure, misery, disgruntlement, non-satisfaction, cheerlessness, dissatisfaction, discomfort, anguish, gloominess, ennui, irritation, joylessness, sourness, inquietude, discontent, uneasiness, anxiety, displeasure, unhappiness
- Seven years of being a good little boy got you nothing but the promise of present and future frustration. - "This Crowded Earth", Robert Bloch.
- For a long time they bore with patience the betrayal and frustration of their plans. - "A Struggle for Rome, Vol. 2 (of 3)", Felix Dahn.
- Anger was blazing in Paul's voice now, bitterness and frustration. - "Martyr", Alan Edward Nourse.