GRAEFE'S KNIFE'S SPOTS
\ɡɹˈiːfs nˈa͡ɪfz spˈɒts], \ɡɹˈiːfs nˈaɪfz spˈɒts], \ɡ_ɹ_ˈiː_f_s n_ˈaɪ_f_z s_p_ˈɒ_t_s]\
Definitions of GRAEFE'S KNIFE'S SPOTS
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.