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Definition of grievous : 1. Causing grief or sorrow; painful; afflictive; hard to bear; offensive; harmful.
2. Characterized by great atrocity; heinous; aggravated; flagitious; as, a grievous sin.
3. Full of, or expressing, grief; showing great sorrow or affliction; as, a grievous cry.

Synonyms:

rough, heartbreaking, backbreaking, parlous, solemn, large, frightful, cogent, laboured, sober, obese, flagitious, heartrending, fleshy, unsafe, sorrowful, afflicting, risky, dire, corpulent, heinous, deplorable, intemperate, desperate, pathetic, clayey, happy, horrible, searing, inhuman, stark, regrettable, wicked, venturesome, harsh, spartan, horrifying, enceinte, disturbing, unplayful, dense, rigorous, unhealthy, telling, important, rotund, awful, critical, punishing, big, doleful, weighty, with child, heavy, ugly, terrible, rugged, lamentable, sullen, laborious, tough, dangerous, labored, stiff, unspeakable, sad, good, hazardous, distressing, lowering, sedate, disquieting, evil, upsetting, leaden, ponderous, grim, outrageous, of import, great, toilsome, gravid, hardhanded, torturous, murderous, monstrous, grave, villainous, rueful, brutal, onerous, overweight, galling, extreme, wakeless, weighed down, help, knockout, operose, life-threatening, expectant, grotesque, cloggy, atrocious, austere, dreadful, lumbering, abominable, jeopardizing, gruelling, serious, menacing, mournful, threatening, sound, profound, impenetrable, flagrant, sonorous, dismal, dolorous, stern

adverse (part of speech: adjective)

disastrous, detrimental, unfriendly, unfavorable, tragic, antipathetic, inauspicious, adverse, difficult, hard, unpropitious, perilous, opposing, calamitous, untoward, unfortunate, unlucky, catastrophic

painful (part of speech: adjective)

disagreeable, troublesome, insufferable, sore, hurtful, anguishing, crushing, harrowing, burdensome, uncomfortable, stinging, annoying, bitter, bothersome, trying, odious, piercing, chafing, grueling, horrendous, irksome, withering, biting, painful, severe, distressful, torturing, smarting, tormenting, cruel, aching, arduous, stabbing, miserable, unbearable, sharp, throbbing, gnawing, unpleasant, cramping, besetting, aggravating, excruciating, inflaming, irritating, oppressive, offensive, wrenching, agonizing, cutting, woeful, acute

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