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Definition of guinea pig:

  1. A small animal of the rodent or gnawing order, covered with white, red, and black patches; a cony.

Synonyms:

issue, antelope, content, vitrine, study, display case, compositor's case, field, event, case, eccentric, font, topic, subject area, face, grammatical case, subject, matter, bear, ass, bailiwick, character, bat, pillow slip, dissect, slip, detect, type, shell, typeface, bison, lawsuit, discipline, causa, empirical, typesetter's case, depicted object, biopiracy, chromatography, suit, fount, national, animal rights, sheath, Cavia Cobaya, instance, black bear, bighorn sheep, badger, field of study, showcase, cause, angora, subject field, control, pillowcase, caseful, anatomize, anteater, theme, example, detection, casing, double-blind.