HE'PAR SINISTRUM

\hiːpˈɑː sˈɪnɪstɹəm], \hiːpˈɑː sˈɪnɪstɹəm], \h_iː_p_ˈɑː s_ˈɪ_n_ɪ_s_t_ɹ_ə_m]\

Definitions of HE'PAR SINISTRUM

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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