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Definition of idiosyncrasy : A peculiarity of physical or mental constitution or temperament; a characteristic belonging to, and distinguishing, an individual; characteristic susceptibility; idiocrasy; eccentricity.

Synonyms:

pose, affectedness, foible, habit, usual, affectation

forte, cachet, individuality, quirk, quality, property, discriminant, particularity, specialization, definiteness, characteristic, hallmark, stamp, flavor, trait, mannerism, specialty, way, feature, figure, keynote, mark

curiosity, impropriety, funniness, incongruity, exception, quirkiness, divergence, inconsistency, incompatibility, oddity, strangeness, difference, unfamiliarity, peculiarity, aberrance, nonconformity, derangement, uniqueness, outlandishness, deviation, anomaly, aberration, singularity, uncommonness, irregularity, unconventionality, eccentricity, abnormality, freakishness

Usage examples:

• This idiosyncrasy of Gen. - "The Struggle for Missouri", John McElroy.
• I have no fable at hand to explain what seems the special preference of the birds for this garden; it is possibly an idiosyncrasy, something like that of the cats which make Trajan's Forum their favorite resort. - "Roman Holidays and Others", W. D. Howells.
• Age, idiosyncrasy, tolerance, and disease, all exert modifying influences on the action of a poison. - "Aids to Forensic Medicine and Toxicology", W. G. Aitchison Robertson.