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Definition of indefatigable : Incapable of being fatigued; not readily exhausted; unremitting in labor or effort; untiring; unwearying; not yielding to fatigue; as, indefatigable exertions, perseverance, application.

Synonyms:

energetic, tired, hardworking, unwearying, active, unfailing, weariless, untiring, inexhaustible, unwearied, continue, industrious

habitual, unvarying, continuing, perpetual, continuous, robot-like, level, monotonous, straight, nonstop, unending, cyclical, sequential, uniform, unremitting, everlasting, undeviating, consecutive, seamless, connected, homogeneous, incessant, undying, unceasing, repeated, invariable, perennial, recurrent, regular, continual, ceaseless, unbroken, even, interminable, endless, coherent, repetitive, featureless, un-intermittent, unchanging, flat, monolithic, gapless, consistent

headstrong, decided, implacable, unflinching, intent, courageous, staunch, steely, dedicated, bullheaded, tireless, willing, valiant, loyal, spunky, bold, ruthless, devoted, firm, reliable, resolute, relentless, zealous, dauntless, set, dogged, plucky, steady, faithful, insistent, iron-willed, strong-minded, resolved, inexorable, fearless, uncompromising, deliberate, serious, stern, unshakeable, earnest, constant, thorough, unyielding, committed, stubborn, true, unchangeable, decisive, diligent, tough, strong-willed, hearty, unbending, determined

hard, stiff, bulldogged, undaunted, obstinate, flintlike, fervent, strong, obdurate, stony

indomitable, brave, persistent, patient, stoical, steadfast, unflagging, surviving, enduring, lasting, tenacious, unwavering, abiding, persevering, unfaltering

Usage examples:

• In a short time the indefatigable Cimarrons had built a fine large hut of cane: one room for myself and the baggage, a large assembly- room for the people, and a special apartment for cooking. - "The Former Philippines thru Foreign Eyes", Tomás de Comyn Fedor Jagor Rudolf Ludwig Carl Virchow Charles Wilkes.
• Without the use of the tools or the machinery familiar to the European, each individual could have done little; but acting in large masses, and under a common direction, they were enabled by indefatigable perseverance to achieve results, to have attempted which might have filled even the European with dismay. - "History-of-the-Conquest-of-Peru-with-a-preliminary-view-of-the-civilization-of-the-Incas", Prescott, William Hickling.
• " I hear they's a new hasher at Bill Lainey's hotel," pursued the indefatigable Jimmie. - "The Heart of the Range", William Patterson White.