INSTANTIATE
\ɪnstˈanʃɪˌe͡ɪt], \ɪnstˈanʃɪˌeɪt], \ɪ_n_s_t_ˈa_n_ʃ_ɪ__ˌeɪ_t]\
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.