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Definition of iota : 1. A very small quantity or degree; a jot; a particle.
2. The ninth letter of the Greek alphabet corresponding with the English i.

Synonyms:

molecule, rag, scruple, scintilla, tatter, smidgeon, element, tittle, dot, big, rap, dram, tag end, trifle, fragment, smidge, hoot, tag, minim, spot, damn, diddly, ounce, ort, corpuscle, smidgin, jot

grain, atom, mite, smidgen, shred, scrap, dab, pittance, smithereen, crumb, bit, granule, touch, flyspeck, trace, morsel, speck, whit, dash, drop, modicum, particle

Usage examples:

• The majority in the assembly were determined not to abate one iota of their pretensions, which now included the control of the casual and territorial revenues; and no provision whatever was made for four years for the payment of the public service. - "Canada under British Rule 1760-1900", John G. Bourinot.
• Could he explain to Dr. Webber that he knew this simply because in some way he had sensed them, and traced them, and discovered them; that he had not one iota of proof, except that he was being followed by them, hunted by them, even now, in a room in the Old City, waiting for them to strike him down? - "The Dark Door", Alan Edward Nourse.
• She shut her eyes and put every iota of her mind to work on the problem of finding something- anything- that could be done to help this doomed world and to show that big, overbearing jerk of a Garlock that she was a better man than he was. - "The Galaxy Primes", Edward Elmer Smith.