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Definition of irritate:

  1. Excited; heightened.
  2. To excite anger or displeasure in; to provoke; to tease; to exasperate; to annoy; to vex; as, the insolence of a tyrant irritates his subjects.
  3. To increase the action or violence of; to heighten excitement in; to intensify; to stimulate.
  4. To make morbidly excitable, or oversensitive; to fret; as, the skin is irritated by friction; to irritate a wound by a coarse bandage.
  5. To produce irritation in; to stimulate; to cause to contract. See Irritation, n., 2.
  6. To render null and void.

Synonyms:

inconvenience oneself, jaw, trouble oneself, feelings, get, lambast, call down, disoblige, vex, reprimand, dun, chide, perplex, stick, redden, gall, rile, fray, stir up, chew out, worry, tantalize, ride, put out, take to task, shake up, itch, have words, dress down, urticate, excoriate, annoy, raise up, twit, access, insult, dumbfound, nonplus, puzzle, gravel, bother, progress to, erupt, nettle, commove, amaze, flummox, bug, chafe, bewilder, help, ruffle, cod, frustrate, wound, baffle, stupefy, rag, discommode, roil, nark, make, scold, berate, agitate, lecture, swell, tantalise, reproof, bawl out, razz, pose, inconvenience, affront, taunt, incommode, call on the carpet, get at, remonstrate, burn, devil, crucify, get to, rebuke, trounce, chew up, lambaste, rally, scratch, mystify, beat, reach.

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