Definition of irritation :
1. A condition of morbid excitability or oversensitiveness of an organ or part of the body; a state in which the application of ordinary stimuli produces pain or excessive or vitiated action.
2. The act of exciting, or the condition of being excited to action, by stimulation; -- as, the condition of an organ of sense, when its nerve is affected by some external body; esp., the act of exciting muscle fibers to contraction, by artificial stimulation; as, the irritation of a motor nerve by electricity; also, the condition of a muscle and nerve, under such stimulation.
3. The act of irritating, or exciting, or the state of being irritated; excitement; stimulation, usually of an undue and uncomfortable kind; especially, excitement of anger or passion; provocation; annoyance; anger.
mood, pain in the neck, rage, anger, toughness, fervour, impatience, menace, rawness, annoying, aggravator, bothering, peeve, drag, plague, nuisance, excitement, pest, biliousness, fervor, choler, joke, concern, feelings, pain in the ass, irritability, fretfulness, tenderness, pip, outrage, besetment, surliness, fury, temper, asperity, stress, aggro, humour, upset, calamity, neuralgia, animosity, peevishness, snappishness, incitement, help, eina, botheration, irritant, pestering, incitation, humor, worry, pettishness, excitation, chafe, passion, innervation
discontentment (part of speech: noun)
displeasure, despondence, sourness, joylessness, inquietude, anxiety, ennui, angst, disgruntlement, disquiet, unhappiness, gloominess, frustration, boredom, wretchedness, non-satisfaction, uneasiness, cheerlessness
pain (part of speech: noun)
grief, spasm, headache, burn, hurt, stitch, painfulness, suffering, wound, stab, malaise, earache, smarting, cramp, bite, crick, sting, migraine, pain, pang, rack, torment, back-ache, infliction, gripe, distress, sore, agony, ache, affliction, injury, anguish, wrench, throe, torture, misery, discomfort, inflammation, bruise, throb, chafing
aggravation (part of speech: noun)
painfulness (part of speech: noun)
aggravation, severity, distressfulness, uncomfortableness, woefulness, acuteness, annoyingness, odiousness, oppressiveness, unpleasantness, irksomeness, grievousness, offensiveness, arduousness, cruelty, hurtfulness
sensitivity (part of speech: noun)
resentment (part of speech: noun)
hard feelings, acerbity, ill humor, soreness, resentment, rancor, bitterness, pique, spite, bile, antagonism, huffiness, umbrage, envy, vexation, infuriation, sullenness, wrath, discontent, dissatisfaction, indignation, offense
- He spoke with an ill- subdued irritation I knew not how to soothe. - "Daisy Burns (Volume 2)", Julia Kavanagh.
- Gaiety turned to irritation, irritation to anger and fear. - "The Celestial Omnibus and other Stories", E. M. Forster.
- Lady Niton looked at her with mingled amusement and irritation. - "The Testing of Diana Mallory", Mrs. Humphry Ward.