JEFFERSONLA

\d͡ʒˈɛfəsˌɒnlə], \d‍ʒˈɛfəsˌɒnlə], \dʒ_ˈɛ_f_ə_s_ˌɒ_n_l_ə]\

Definitions of JEFFERSONLA

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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