JOFFROY'S REFLEX'S SIGN

\d͡ʒˈɒfɹɔ͡ɪz ɹˈiːflɛksɪz sˈa͡ɪn], \d‍ʒˈɒfɹɔ‍ɪz ɹˈiːflɛksɪz sˈa‍ɪn], \dʒ_ˈɒ_f_ɹ_ɔɪ_z ɹ_ˈiː_f_l_ɛ_k_s_ɪ_z s_ˈaɪ_n]\

Definitions of JOFFROY'S REFLEX'S SIGN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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