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Definition of knob : 1. A hard protuberance; a hard swelling or rising; a bunch; a lump; as, a knob in the flesh, or on a bone.
2. A knoblike ornament or handle; as, the knob of a lock, door, or drawer.
3. A rounded hill or mountain; as, the Pilot Knob.
4. See Knop.
5. To grow into knobs or bunches; to become knobbed.

Synonyms:

bump, jut, hirer, beaver, doorstop, protuberance, bottom, doorknocker, trace, clitoris, lump, lymph node, pommel, thickener, cervix, fragment, console, doorplate, confines, boner, master switch, cock, lymph gland, door, chief, inspissation, balls, pause, bits, saddlebow, bevel, protrusion, party boss, fast forward, latch, panel, edge, thickening, guest, bollocks, gaffer, taster, piece, cervical, projection, doorpost, fraction, node, nub, lever, bulge, knot, control, sample, corner, political boss, base, release, foreman, bit, apex, doorstep, client, a little, honcho, leaf node, boss, dial, cojones, back, hump, arch, doorbell, hint, convex, doorjamb, a bit, overhang, brim

handle, stock, brace, knocker, lug, crank, trigger, doorknob, spindle, pull, shank, brake

Usage examples:

• Jig turned the knob cautiously and slipped out into the living room. - "The Rangeland Avenger", Max Brand.
• He leaned right back until his body was level with the horse's, then changing his whip quickly, he hit backwards, bringing the heavy knob hard on the root of the tail. - "The Sweep Winner", Nat Gould.
• He has his hand on the knob, when a new thought comes to him. - "Torchy", Sewell Ford.