LOMBARDI'S SIGN
\ləmbˈɑːdɪz sˈa͡ɪn], \ləmbˈɑːdɪz sˈaɪn], \l_ə_m_b_ˈɑː_d_ɪ_z s_ˈaɪ_n]\
Definitions of LOMBARDI'S SIGN
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.