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Definition of malice : 1. Any wicked or mischievous intention of the mind; a depraved inclination to mischief; an intention to vex, annoy, or injure another person, or to do a wrongful act without just cause or cause or excuse; a wanton disregard of the rights or safety of others; willfulness.
2. Enmity of heart; malevolence; ill will; a spirit delighting in harm or misfortune to another; a disposition to injure another; a malignant design of evil.
3. To regard with extreme ill will.

Synonyms:

despitefulness, cat bite, ill will, implacability, malignance, dirt, attitude, acerbity, pure cussedness, malignity, poisonousness, grudge, mordacity, spite, ill-feeling, umbrage, malevolency, bitchiness, venomousness

bad blood, coldness, malevolence, contrariety, contention, discordance, alienation, friction, hard feelings, quarrelsomeness, unfriendliness, hostility, conflict, polarity, incompatibility, coolness, surliness, combativeness, inharmoniousness, opposition, resentment, spitefulness, tension, inimicality, adverseness, dislike, averseness

hatefulness, corrosiveness, meanness, malignancy, evil, cattiness, sinisterness, maliciousness, venom, viciousness, virulence, wickedness, foulness, ill nature, hurtfulness, bane, nastiness

aversion, disgust, abomination, loathing, rancor, enmity, antipathy, disaffection, repulsion, acrimony, bitterness, hate, repugnance, antagonism, hatred, wrath, animosity, abhorrence, detestation

Usage examples:

• The laughing malice of that book had so confused me for some days that I had begun to feel that even St. Paul's, a blue bubble floating over London on the stream of Time, might vanish, as bubbles will. - "Waiting for Daylight", Henry Major Tomlinson.
• Her smile was full of friendly malice. - "The Blood Red Dawn", Charles Caldwell Dobie.
• This is not a moment to bear malice; and I freely pardon you all and everything. - "Jack Tier or The Florida Reef", James Fenimore Cooper.