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Definition of manipulation : 1. Artful management; as, the manipulation of political bodies; sometimes, a management or treatment for purposes of deception or fraud.
2. The act or process of manipulating, or the state of being manipulated; the act of handling work by hand; use of the hands, in an artistic or skillful manner, in science or art.
3. The use of the hands in mesmeric operations.

Synonyms:

habit, usage, economic consumption, utilization, administration, usance, function, treatment, handling, employment, purpose, use of goods and services, direction, exercise, utilisation, use, enjoyment, consumption, role

pawing, contact, tangibility, plying, rubbing, touch, feeling, palpation, twiddle

Usage examples:

• Patience and some skill in manipulation is always required for this sort of experiment. - "Letters of a Radio-Engineer to His Son", John Mills.
• He wanted to get everything for nothing, afraid of the use that Aristide might make of a damning confession, and also relying for success on his manipulation of the cards. - "The Joyous Adventures of Aristide Pujol", William J. Locke.
• She is the intelligent and expert and self- possessed one of them all; they have only to leave everything to her light manipulation, and the awkwardness- which is theirs, not hers- is surmounted. - "The Craft of Fiction", Percy Lubbock.