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Definition of massacre : 1. Murder.
2. The killing of a considerable number of human beings under circumstances of atrocity or cruelty, or contrary to the usages of civilized people; as, the massacre on St. Bartholomew's Day.
3. To kill in considerable numbers where much resistance can not be made; to kill with indiscriminate violence, without necessity, and contrary to the usages of nations; to butcher; to slaughter; - limited to the killing of human beings.

Synonyms:

whipping, despatch, drubbing, abattoir, put to death, mass murder, trouncing, pogrom, thrashing, walloping, help, butchery, bloodletting, mow down, beating, shambles, vanquishment, bloodshed, trimming, defeat, carnage, rout, bloodbath, overthrow, slaughterhouse, licking, study at slaughter, debacle, win, dusting

chill, dispatch, remove, eliminate, drown, exterminate, assassinate, ice, kill, slay, suffocate, liquidate, do in, slaughter, murder, execute, snuff, do away with, purge, sacrifice, smite, smother, strangle, put to sleep, asphyxiate, hang, butcher

assassination, removal, execution, slaying, strangulation, asphyxiation, butchering, liquidation, purging, snuffing, killing, extermination, manslaughter, dispatching, elimination, hanging

Usage examples:

• They cannot, whatever is said of them, be on an errand of massacre. - "Septimius Felton or, The Elixir of Life", Nathaniel Hawthorne.
• A few escaped down the river, but only four men survived to tell the story of the massacre. - "The Great Events by Famous Historians, Vol. 17", Charles Francis Horne.
• Just a animated massacre in pants. - "Hopalong Cassidy", Clarence E. Mulford.