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Definition of middle : 1. Equally distant from the extreme either of a number of things or of one thing; mean; medial; as, the middle house in a row; a middle rank or station in life; flowers of middle summer; men of middle age.
2. Intermediate; intervening.
3. The point or part equally distant from the extremities or exterior limits, as of a line, a surface, or a solid; an intervening point or part in space, time, or order of series; the midst; central portion
4. the waist.

Synonyms:

inwardness, diaphragm, fondness, eye, spunk, nitty-gritty, shopping mall, essence, mettle, mall, midriff, spirit, edge, substance, pump, heart and soul, nerve, centre of attention, tenderness, pith, meat, plaza, center of attention, shopping center, nerve centre, midsection, gist, bosom, center field, nerve center, centre, affection, ticker, centerfield, warmheartedness, snapper, shopping centre, philia, mediate, optic, warmness, in-between, sum, affectionateness, oculus

innermost, main, midway, interior, focal

medial, central, halfway, median, intermediate, mediocrity, hub, bisecting, nub, marrow, mean, nucleus, midpoint, halfway point, middle-of-the-road, centralized, axis, midst, pivot, average, equidistant, middling, mediocre, epicenter, bisection, medium, mid, core, nuclear, half, geocentric, midmost, kernel, heart, pivotal, axial, mezzo, center, half-and-half

centrality, focus

Usage examples:

• I gallopped off, and reached home in the middle of the night. - "Adventures in the Philippine Islands", Paul P. de La Gironière.
• Her middle name had caught his attention also. - "A Man's Hearth", Eleanor M. Ingram.
• A middle course may be thought more convenient. - "Secret Diplomatic History of The Eighteenth Century", Karl Marx.