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Definition of nadir:

  1. That point of the heavens, or lower hemisphere, directly opposite the zenith; the inferior pole of the horizon; the point of the celestial sphere directly under the place where we stand.
  2. The lowest point; the time of greatest depression.

Synonyms:

breaking point, rock bottom, milestone, lowest point, zero, depth, peak, highlight, the moment of truth, the point of no return, turning point, watershed, low-water mark, crossroads, climax, bedrock, opposite.

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