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Definition of off : 1. Away; begone; - a command to depart.
2. Denoting a different direction; not on or towards: away; as, to look off.
3. Denoting a leaving, abandonment, departure, abatement, interruption, or remission; as, the fever goes off; the pain goes off; the game is off; all bets are off.
4. Denoting distance or separation; as, the house is a mile off.
5. Denoting opposition or negation.
6. Denoting the action of removing or separating; separation; as, to take off the hat or cloak; to cut off, to pare off, to clip off, to peel off, to tear off, to march off, to fly off, and the like.
7. Designating a time when one is not strictly attentive to business or affairs, or is absent from his post, and, hence, a time when affairs are not urgent; as, he took an off day for fishing: an off year in politics.
8. In a general sense, denoting from or away from; as:
9. Not on; away from; as, to be off one's legs or off the bed; two miles off the shore.
10. On the farther side; most distant; on the side of an animal or a team farthest from the driver when he is on foot; in the United States, the right side; as, the off horse or ox in a team, in distinction from the nigh or near horse or ox; the off leg.
11. The side of the field that is on the right of the wicket keeper.

Synonyms:

sullen, get rid of, rack up, maniac, far, initiated, do in, touched, despatch, shoot, take away, fruity, above, slow, knock off, murder, waste, dark, bonkers, collide with, begun, discharge, help, beside, lunatic, come to, inactive, pip, cracked, withdraw, tally, take out, forward, soured, moonstruck, reach, put away, strike, arrive at, wrong, send off, unsatisfactory, wrap up, afar, mop up, subnormal, slack, unsound, mangle, glum, run into, morose, untrue, rancid, unbalanced, bump off, insane, polish off, cancelled, glowering, out, off-duty, erring, demented, sour, distraught, moody, like, originated, rub out, appreciate, beneath, make, stumble, dull, gain, finish, kill, gone, mutilate, soft, daffy, distant, clear up, off-key, eat up, fallacious, take pleasure in, returning, by, dotty, absent, transfer, down, cuckoo, attain, confused, mistaken, disconnected, brainsick, coming, get through, remove, nuts, non compos mentis, inaccurate, batty, finish up, increase, ahead, zap, gaga, away, screwy, move out, liquidate, erroneous, bananas, false, loco, take, unemployed, complete, finish off, hit, behind, disordered, sluggish, unproductive, wipe out, nutty, score, mad, incorrect, maniacal, substandard, saturnine, buggy, dour, crackers, correct, dispatch, destroy, here, mentally ill, sane, wacky, removed, impinge on, turned, slay, aside, daft, onward, loony, forth, poor

fey, quirky, curious, funny, uncustomary, bizarre, unusual, different, incompatible, incongruous, unconventional, freakish, aberrant, un-ordinary, novel, divergent, oddity, crosspatch, crazy, irregular, deviant, outlandish, atypical, odd, singular, nonconforming, extraordinary, uncommon, deranged, oddball, queer, improper, anomalous, idiosyncratic, misfit, strange, eccentric, mismatch, out of the ordinary, untypical, erratic, unique, exceptional, abnormal, peculiar, inconsistent, unfamiliar

Usage examples:

• The man and woman who had the head, did not come off again. - "A Voyage Towards the South Pole and Round the World, Volume 1", James Cook.
• " That must come off," he said. - "The Boy Scouts on a Submarine", Captain John Blaine.
• I thought of it right off. - "Penny Nichols Finds a Clue", Joan Clark.