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Definition of operation : 1. Any methodical action of the hand, or of the hand with instruments, on the human body, to produce a curative or remedial effect, as in amputation, etc.
2. Effect produced; influence.
3. Something to be done; some transformation to be made upon quantities, the transformation being indicated either by rules or symbols.
4. That which is operated or accomplished; an effect brought about in accordance with a definite plan; as, military or naval operations.
5. The act or process of operating; agency; the exertion of power, physical, mechanical, or moral.
6. The method of working; mode of action.

Synonyms:

account, accomplishment, outgrowth, carrying out, technique, post, bombardment, mode, surgical process, effect, intendance, handling, superintendency, working, acquisition, transplant, government, the biz, advancement, enforcement, supervision, subroutine, doing, summons, governance, venture, wear, management, process, consumption, colostomy, implementation, physical process, removal, mental process, brief, agent, achievement, air raid, carrying into action, administration, public presentation, conveyance, cut in, go on, direction, functioning, procedure, used, anchor, way, maintenance, handiwork, affiliate, manipulation, bombing, tactic, air strike, mathematical process, presidency, guidance, cognitive process, the Blitz, method, job, play, dissection, blitzkrieg, big business, military operation, manner, barrage, charge, control, circumcision, blue chip, engagement, exploitation, cope, stewardship, adoption, superintendence, machine, system, means, basis, cognitive operation, cesarean, operating theatre, section, agency, workmanship, routine, course, blast, medicine, base, angioplasty, appendage, bypass, thing, subprogram, business, plan, consummation, abortion, run, appendectomy, come on, operating room, transaction, progress, controlling, execution, ordering, move, progression, into operation, blitz, attack, operate, regulation, operating theater, running, excision, work, feat, demonstration, proceeding, exploit, assignment, surgical operation, unconscious process, detail, D and C, care, act, surgical procedure, caesarean, formula, C-section, reaction, surgery, mathematical operation, oversight

exercise, labor, action, behavior, endeavor, activity, enterprise, effort, conduct, movement, deed, performance, practice, motion

function, application, use, service, usage, utility, employment, exertion, utilization

Usage examples:

• A minute or two later the situation had changed, and she knew it afterwards to have been by the subtle operation of Kate. - "The Wings of the Dove, Volume 1 of 2", Henry James.
• In such cases immediate operation is indicated. - "Manual of Surgery Volume Second: Extremities--Head--Neck. Sixth Edition.", Alexander Miles Alexis Thomson.
• He couldn't have looked more relieved over the successful finish of a difficult operation. - "Mary Wollaston", Henry Kitchell Webster.