PHASCOLOTHERIUM
\fˌaskələðˈi͡əɹɪəm], \fˌaskələðˈiəɹɪəm], \f_ˌa_s_k_ə_l_ə_ð_ˈiə_ɹ_ɪ__ə_m]\
Definitions of PHASCOLOTHERIUM
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.