irritation, annoyance, agony, joke, menace, calamity, eina, pang, pest, anguish, neuralgia, drag, peeve, distress, irritant, vexation, discomfort, ache, pain.
I think that the first thing I said to you was that this strike, if it took place, would be like the pinprick
on an elephant's hide.
Somehow he felt oddly reluctant to inflict even a pinprick
of pain on this particular patient.