PRINCIPALNESS
\pɹˈɪnsɪpə͡lnəs], \pɹˈɪnsɪpəlnəs], \p_ɹ_ˈɪ_n_s_ɪ_p_əl_n_ə_s]\
Definitions of PRINCIPALNESS
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.