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Definition of quarto : 1. Having four leaves to the sheet; of the form or size of a quarto.
2. Originally, a book of the size of the fourth of sheet of printing paper; a size leaves; in present usage, a book of a square or nearly square form, and usually of large size.

Synonyms:

quaternary, quadrilateral, rectangular, square, quadrangular, quartet, quad, four

Usage examples:

• It is impossible not to be amazed when we think that in the short space of thirty years this man wrote and published, on the truths of the Spiritual World, twenty- five quarto volumes, composed in Latin, of which the shortest has five hundred pages, all of them printed in small type. - "Seraphita", Honore de Balzac.
• It was a small quarto, a. - "Greene Ferne Farm", Richard Jefferies.
• Then my eyes turned to an open quarto book. - "The Quest of the Sacred Slipper", Sax Rohmer.