REAGGRAVATION

\ɹˌiːˌaɡɹɐvˈe͡ɪʃən], \ɹˌiːˌaɡɹɐvˈe‍ɪʃən], \ɹ_ˌiː__ˌa_ɡ_ɹ_ɐ_v_ˈeɪ_ʃ_ə_n]\

Definitions of REAGGRAVATION

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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