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Definition of resignation : 1. The act of resigning or giving up, as a claim, possession, office, or the like; surrender; as, the resignation of a crown or comission.
2. The state of being resigned or submissive; quiet or patient submission; unresisting acquiescence; as, resignation to the will and providence of God.

Synonyms:

leniency, calmness, patience, demission, departure, resistance, fall, humility, keep, endurance, composure, long-suffering, waiver, giving up, accept, yielding, quitclaim, tolerance, forbearance, fortitude, sufferance, docility

defection, abdication, vacation, discontinuation, tergiversation, relinquishment, apostasy, surrender, desertion, abandonment, withdrawal

dereliction, release, renunciation, disclamation, capitulation

discontinuance, rejection, cessation, acceptance, renouncement, termination, retirement

conformity, obeisance, homage, deference, acquiescence, meekness, fulfillment, consent, compliance, assent, submission, respect, obedience, willingness, affirmation, concurrence, fealty, conformance, observance, submissiveness, servility, agreement, adherence, genuflection

Usage examples:

• Daniel Burton, with a helpless gesture that expressed embarrassment, dismay, bewilderment, and resignation, threw up both hands and settled back in his chair. - "Dawn", Eleanor H. Porter.
• " As the young lady pleases," said the old man, with a look of resignation. - "The Golden House", Mrs. Woods Baker.
• With the same left hand she made a gesture of resignation. - "Greener Than You Think", Ward Moore.