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Definition of spay:

  1. To extirpate the ovaries of; to castrate, said of a female animal.

Synonyms:

modify, the N.S.P.C.A., rich, vary, bowdlerise, sex, fix, shorten, expurgate, demasculinize, alter, vaccinate, the ASPCA, neuter, change, falsify, dock, interpolate, unsex, castrate, vet, demasculinise, bowdlerize, reproduction.