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Definition of tranquillise:

  1. To quiet; to calm or soothe; to allay agitation.

Synonyms:

ease, tranquillize, allay, cool it, sedate, relieve, silence, hush up, lull, quiesce, quiet, cool off, settle down, hush, becalm, simmer down, shut up, calm, calm down, quieten, steady, pipe down, still, chill out, quiet down, tranquilize.