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Definition of ulcer : 1. A solution of continuity in any of the soft parts of the body, discharging purulent matter, found on a surface, especially one of the natural surfaces of the body, and originating generally in a constitutional disorder; a sore discharging pus. It is distinguished from an abscess, which has its beginning, at least, in the depth of the tissues.
2. Fig.: Anything that festers and corrupts like an open sore; a vice in character.
3. To ulcerate.

Synonyms:

fistula, open sore, abscess, ulceration, lesion, canker, boil, sore, focal infection, running sore

Usage examples:

• But never lose sight of the fact that unless you have a definite and worthy purpose, to attain which you keep your good time subordinate, that good time will have the same relation to genuine pleasure that the throbbings of an ulcer have to the healthy action of the heart. - "Men in the Making", Ambrose Shepherd.
• You know how painful an ulcer is anywhere- say on your lip- now for over two years this ulceration had been burning its way in the intestines. - "The Eulogy of Richard Jefferies", Walter Besant.
• So, if there be a sore, or festering ulcer, the atoms which are thrown off attract similar atoms, so as to reproduce the ulcer or sore, and thus prevent the disease from getting well of itself until it has worn itself out. - "The-Light-of-Egypt-or-the-science-of-the-soul-and-the-stars-Volume-2", Burgoyne, Thomas H..