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Definition of vitiate:

  1. To cause to fail of effect, either wholly or in part; to make void; to destroy, as the validity or binding force of an instrument or transaction; to annul; as, any undue influence exerted on a jury vitiates their verdict; fraud vitiates a contract.
  2. To make vicious, faulty, or imperfect; to render defective; to injure the substance or qualities of; to impair; to contaminate; to spoil; as, exaggeration vitiates a style of writing; sewer gas vitiates the air.

Synonyms:

foil, deject, buy, go bad, demoralise, recant, deflower, bobble, tarnish, cosset, thwart, rape, misguide, evacuate, void, taint, deny, lead astray, fumble, featherbed, animalize, debauch, defile, abolish, blow, impair, annul, subvert, infect, convolute, frustrate, bribe, dispirit, muff, stretch, foul up, bollix, help, flub, disserve, alloy, mishandle, bollocks up, befoul, invalidate, violate, muck up, debase, soil, bastardize, cast down, outrage, canker, ruin, clean, bumble, ball up, annihilate, bollocks, cocker, mollycoddle, bollix up, rescind, baffle, cross, detract from, pamper, quash, blemish, sabotage, indulge, negate, continue, mutilate, bring down, set aside, revoke, baby, pollute, spoil, mar, fluff, better, pervert, coddle, misuse, twist around, bestialize, itch, prejudice, cancel, botch up, harm, get down, despoil, misaddress, sully, dilute, countermine, depress, hurt, grease one's palms, empty, avoid, bodge, corrupt, deprave, profane, dismay, misdirect, brutalize, extinguish, plunder, stain, overturn, louse up, contaminate, injure, nullify, demoralize, overthrow, sophisticate, blight, mislead, abuse, cloud, bilk, bungle, flaw, counteract, damage, load, mess up.

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