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Definition of Against:

Abreast; opposite to; facing; towards; as, against the mouth of a river; - in this sense often preceded by over.
By of before the time that; in preparation for; so as to be ready for the time when.
From an opposite direction so as to strike or come in contact with; in contact with; upon; as, hail beats against the roof.
In opposition to, whether the opposition is of sentiment or of action; on the other side; counter to; in contrariety to; hence, adverse to; as, against reason; against law; to run a race against time.

Synonyms:

toward, on, upon, next, into.

opposite (part of speech: adjective)
- corresponding,
- abreast,
- facing
diametric (part of speech: adjective)
- opposite,
- diametric,
- polar,
- reverse,
- converse,
- inverse,
- adversarial,
- across

Usage examples:

But I say nothing against Mrs. Fenwick.

- "Somehow Good", William de Morgan.
" She has never spoken a word against him- not even to me from whom she never had a secret.

- "The Mettle of the Pasture", James Lane Allen.
I know how much you and Mr. Sefton were against it; but I do not think you would wish me to stay behind.

- "Our Bessie", Rosa Nouchette Carey.