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Definition of exasperation:

  1. Increase of violence or malignity; aggravation; exacerbation.
  2. The act of exasperating or the state of being exasperated; irritation; keen or bitter anger.

Synonyms:

offense, fury, bothering, wrath, temper, animosity, peevishness, anger, impatience, passion, pain, rage, pettishness, choler, pestering, botheration, feelings, fretfulness.

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