FRONTOTEMPORAL LOBAR DEGENERATION
\fɹˈʌntə͡ʊtmpəɹə͡l lˈə͡ʊbɑː dɪd͡ʒˌɛnəɹˈe͡ɪʃən], \fɹˈʌntəʊtmpəɹəl lˈəʊbɑː dɪdʒˌɛnəɹˈeɪʃən], \f_ɹ_ˈʌ_n_t_əʊ_t_m_p_ə_ɹ_əl l_ˈəʊ_b_ɑː d_ɪ_dʒ_ˌɛ_n_ə_ɹ_ˈeɪ_ʃ_ə_n]\
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An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.