GRANISETRON
\ɡɹˈana͡ɪstɹˌɒn], \ɡɹˈanaɪstɹˌɒn], \ɡ_ɹ_ˈa_n_aɪ_s_t_ɹ_ˌɒ_n]\
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A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.